Lineage specific role of Ship1 in development of allergic airway inflammation
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چکیده
منابع مشابه
Lineage specific role of Ship1 in development of allergic airway inflammation
Background The PI3K pathway is a potent mediator of several functions associated with asthma pathogenesis, including supporting leukocyte survival, activation, migration and cytokine release. Proper negative regulation of this pathway is integral in order to restrict overactive immune responses. Negative regulation of PI3K is predominantly controlled by the lipid phosphatases PTEN and SHIP-1. I...
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ژورنال
عنوان ژورنال: Allergy, Asthma & Clinical Immunology
سال: 2014
ISSN: 1710-1492
DOI: 10.1186/1710-1492-10-s2-a56